Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment

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Abstract

Exposure to nanoparticles has presented potential risks to human cardiorespiratory systems. Pulmonary retention and extrapulmonary redistribution of inhaled nanoparticles have been considered to be important contributing factors of cardiorespiratory diseases. In the present work, 22-nm 59Fe2O3 nanoparticles (radioactive isotope 59

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Zhu, M. T., Feng, W. Y., Wang, Y., Wang, B., Wang, M., Ouyang, H., … Chai, Z. F. (2009). Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment. Toxicological Sciences, 107(2), 342–351. https://doi.org/10.1093/toxsci/kfn245

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