A SO2F2 mediated mild, practical, and gram-scale dehydroxylative transforming primary alcohols to quaternary ammonium salts

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Abstract

A simple, practical and gram-scale process for direct transformation of primary alcohols or silyl ethers to ammonium salts was developed. This method has the feathers of easy work-up (a simple filtration), mild condition, high yield, great practicality and robustness. And the application of the ammonium salts in Suzuki coupling reaction was also accomplished.

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Zhao, C., Zha, G. F., Fang, W. Y., Alharbi, N. S., & Qin, H. L. (2019). A SO2F2 mediated mild, practical, and gram-scale dehydroxylative transforming primary alcohols to quaternary ammonium salts. Tetrahedron, 75(33), 4648–4656. https://doi.org/10.1016/j.tet.2019.07.007

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