Human acetylator polymorphism: Estimate of allele frequency in Libya and details of global distribution

Abstract

Acetylator phenotyping by means of a sulphadimidine test revealed 65% of Libyan Arabs to be slow acetylators. Hence the frequency of the allele controlling slow acetylation (A(s)) is estimated as q = 0.81 ± 0.05. This estimate is similar to those previously recorded in European and adjacent Middle Eastern populations.