Abstract
A basic polypeptide that stimulates DNA synthesis and cell division in confluent populations of mouse Balb/c 3T3 cells has been isolated from whole human serum, and has been separated from the heterogenous group of molecules with insulin like activity. This highly purified basic polypeptide has a molecular weight of 1.3 x 104 and an isoelectric point at 9.7. Approximately 107 polypeptide molecules in the growth medium allow the replication of one density inhibited cell.
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CITATION STYLE
Antoniades, H. N., Stathakos, D., & Scher, C. D. (1975). Isolation of a cationic polypeptide from human serum that stimulates proliferation of 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America, 72(7), 2635–2639. https://doi.org/10.1073/pnas.72.7.2635
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