Improvement of halitosis and changes in saliva components after using dentifrices with menthapiperita extract

Abstract

Background/Objectives: The objective of the present study was to evaluate the efficacy of dentifrices containing Menthapiperita extract on the changes in oral condition, halitosis, and saliva components. Methods/Statistical analysis:After recruiting the subjects, they were examined using the Turesky-Quigley-Hein Plaque index and Löe-Silness gingival index. To analyze the volatile sulfur compounds, which are halitosis inducing substances, H2S, CH3SH and (CH3)2S were quantitatively analyzed using Sensor Gas Chromatograph ODSA- P2 (FIS Inc., Hyogo, Japan). For HPLC analysis of organic acids and inorganic ions in saliva, Dionex ion chromatography system (gradient pump, ED 50 conductivity detector) was used. Findings:In the evaluation of plaque index and gingival index, the values decreased from baseline of 1.87±0.66 and 0.57±0.45 to 1.63±0.88 and 0.17±0.12 after 4 weeks, respectively. Measurement of halitosis also showed a total reduction effect of 41.03% after 4 weeks. In the saliva analysis, total organic acid content decreased from baseline of 10.79±9.39 to 3.41±3.18 after 4 weeks, whereas the concentrations of chloride and phosphate increased after 4 weeks. Improvements/Applications: Based on the findings in the present study, it is determined that the dentifrices containing Menthapiperita (MP) extract used in the present study could improve the oral environment.