Improved Titanium Tetrachloride Procedure for Enamine Synthesis. II. Scope of the Reaction.

Abstract

The scope of enamine formation by a procedure where the carbonyl compd. is added to a performed TiCl4-amine complex was investigated with a series of different types of carbonyl compds. and two secondary amines (morpholine and pyrrolidine). The carbonyl compds. include aldehydes, cyclic ketones, and some substituted aryl alkyl ketones the yields of isolted products were 67-100%. [on SciFinder(R)]