Exercise as Medicine in Multiple Sclerosis— Moving Beyond Compensatory Benefits

Abstract

Many studies have shown that physical exercise improves multiple sclerosis (MS) symptoms, including cognition, fatigue, bowel and bladder function, depression, and overall quality of life. However, the pathophysiologic mechanisms responsible for these symptomaticchanges remain elusive. Exercise offers a likely path for addressing progressive MS, nervous system repair, and as a wellness approachfor people with MS. We as a community need to work toward gaining information to establish an evidence-based exercise prescription for peopleliving with MS