Influence of feiliuping No. 2 on platelet surface glycoprotein expression in mid-late stage lung cancer patients

Abstract

OBJECTIVE: To explore the influence of Feiliuping NO. 2 (FLP), a Chinese herbal preparation for reinforcing Qi, nourishing Yin, activating blood circulation and detoxifying, on surface glycoprotein expression (SGPE) and activated condition of platelet in mid-late stage lung cancer patients. METHODS: Changes of platelet surface expression of CD41/CD42a, CD36/TSP, CD62/CD63, CD9 and CD31 were measured before and after FLP treatment by using flow cytometer in 30 cases of mid-late stage lung cancer. RESULTS: The SGPE and activated condition of platelet in mid-late stage lung cancer patients were significantly higher than those of healthy person, and both could be reduced partly by FLP. CONCLUSION: FLP could influence the SGPE and activate condition of platelet in lung cancer patients.