A microbial iron fist to fight tumors

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Abstract

The microbiome is known to affect antitumor immune responses, but how this occurs is unclear. Rhamnose-rich polysaccharides (RHP) from a commensal strain of Lactiplantibacillus plantarum have now been shown to induce iron sequestration by tumor macrophages, thereby limiting tumor growth and promoting antitumor immunity.

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Nobs, S. P., & Elinav, E. (2024, May 1). A microbial iron fist to fight tumors. Nature Immunology. Nature Research. https://doi.org/10.1038/s41590-024-01806-z

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