Skin Barrier Repair in Eczema: A Review of Current Understanding of Pathophysiology and Treatment

Abstract

Atopic dermatitis is an exceedingly common condition that is often difficult to treat. In this review, the pathophysiology and recent developments are discussed to understand how to better treat atopic dermatitis through the improved understanding of the breakdown of the skin barrier in atopic patients. The available treatments that address these barrier defects are discussed in the light of recent publications. © 2012 Springer Science+Business Media, LLC.