HBA1C level and its role on ischemic stroke patients with prediabetes

Abstract

Background. Stroke is the highest cause of death in Indonesia. Impaired glucose tolerance becomes one of the metabolic risk factors that contribute to ischemic stroke. This study will observe the role of HbA1c level on ischemic stroke in “Dr. Sardjito” General Hospital due to limited research data of this aspect in Indonesia. Objective. The objective of this study is to explore the role of HbA1c level on ischemic stroke in prediabetic patients of “Dr. Sardjito” General Hospital, Yogyakarta. Method. This study design is non-experimental, observational study with correlation analysis approach. The research collected 106 data of non-diabetic and prediabetic ischemic stroke patients’ medical records in “Dr. Sardjito” General Hospital, recorded from 2012 until 2015. Result. A Comparison of HbA1c level in prediabetic ischemic stroke patients were significantly higher (p<0.001), com-pared to non-diabetic ischemic stroke patients (mean rank 80.00 vs. 27.00). Multivariate analysis was performed and showed elevated HbA1c level, modified with decreased diastolic blood pressure, associated 70.8% in determining is-chemic stroke in prediabetic patients of “Dr. Sardjito” General Hospital. Conclusion. Elevated HbA1c level, modified with decreased diastolic blood pressure, has significant predisposition role on ischemic stroke patients with prediabetes in “Dr. Sardjito” General Hospital.