Abstract
A series of 1,2,3-triazole derivatives was synthesized from N-phthalimidoalkyl-azides (A1-A4) and alkynes (a-e) under ultrasound irradiation in the presence of CuI, Et3N and DMF as solvent. The present protocol afforded 18 new 1,2,3-triazoles (1-4) in good-to-excellent yields (67-98%). © 2012 Sociedade Brasileira de Quimica.
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Da Silva, M. T., De Oliveira, R. N., Valença, W. O., Barbosa, F. C. G., Da Silva, M. G., & Camara, C. A. (2012). Synthesis of N-substituted phthalimidoalkyl 1H-1,2,3-triazoles: A molecular diversity combining click chemistry and ultrasound irradiation. Journal of the Brazilian Chemical Society, 23(10), 1839–1843. https://doi.org/10.1590/S0103-50532012005000053
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