THE COMPARISON BETWEEN DEFICIT FUNCTIONAL NEUROLOGIST WITH VON WILLEBRAND FACTOR LEVELS IN ACUTE THROMBOTIC STROKE PATIENTS

Abstract

Background. Stroke still becomes one of the most mortality and disability factor in the world. There is limited studies of von Willebrand factor (vWF) and thrombotic stroke, escpecially the relationship between level of vWF and functional neurological deficit. Objective. This study aims to determine the difference between functional neurological deficit; measured by the NIHSS scale with the vWF level. Methods. Design study was cross sectional, sampling by consecutive admission according to inclusion and exclusion criteria. Blood samples were taken for vWF measurement. Patients are divided into two categories, low vWF level (less than 1,31 IU/ml) and high vWF levels (more than or equal than 1,31 IU/ml). Deficit functional neurologist was measured by NIHSS scale. Results. The results was analyzed by chi square. From 80 patients, the result compares the level of NIHSS scale. In grup with mild NIHSS and low vWF levels ( 50 %) higher than grup with mild NIHSS and high vWF levels (27,27 %). In other side, grup with moderate NIHSS and low vWF levels (50 %) more lower than grup with moderate NIHSS and high vWF levels (72,73 %). The difference is not significant statistically (p=0.067). Conclusion. There was no difference between deficit functional neurologist measured by NIHSS scale with von Willebrand factor levels in acute thrombotic stroke patients. Keywords : level of vWF, NIHSS, stroke trombotik.