Hypothalamic-Pituitary-Gonadal (HPG) Axis

  • Janes L
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Abstract

Definition The hypothalamic-pituitary-gonadal axis (HPG axis) is a hormone-regulating mechanism containing three different component structures that operate in a coordinated fashion and which are involved in the regulation of several reproductive and developmental processes in humans and other species. It operates through a feedback loop involving hormones released from the gonads and the pituitary gland and the hypothalamus. Malfunction of the HPG axis is implicated in many reproductive disorders. Understanding of the HPG axis has been critical in developing forms of birth control.

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Janes, L. (2016). Hypothalamic-Pituitary-Gonadal (HPG) Axis. In Encyclopedia of Personality and Individual Differences (pp. 1–2). Springer International Publishing. https://doi.org/10.1007/978-3-319-28099-8_766-1

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