Antibacterial activity of biogenic silver nanoparticles produced by Aspergillus terreus

Abstract

In the present study, Aspergillus terreus used for the biosynthesis of silver nanoparticle. The A. terreus cell free filtrate reacted with silver nitrate, resulting formation of silver nanoparticles (AgNPs). The AgNP was marked by visual analysis, UV-Vis absorption spectroscopy, Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM). The AgNP showed high absorbance at 450 nm in UV-Vis spectroscopy. The TEM micrograph exhibited poly disperse spherical and ellipsoid NPs in the size range from 20-50 nm. The fungus biogenic AgNPs established strong antibacterial activity against Staphylococcus aureus (MRSA), Shigella boydii, Acinetobacter baumanni, Shigella sonnei and Salmonella typhimurium compared with four antibiotics used. Biological way using the microorganisms is a new approach to the secure, less expensive and eco-friendly technique for the synthesis of silver nanoparticles is gaining importance in the field of nano-biotechnology.