The relation between causes and onset time of polyhydramnios

Abstract

The aim of this analysis was to investigate the onset time and significance of maximum volume of polyhydraminios and whether the latter was associated with causes. This was a retrospective cohort study between 2012 and 2014. A total number of 68 singleton pregnancies were analyzed. Gestational age at onset of polyhydramnios was 30.0 ± 2.8 (25-36) weeks in maternal factor, 30.0 ± 3.5 (25-37) weeks in fetal factor, and 32.3 ± 2.0 (27-37) weeks in idiopathic factor. Median of maximum amniotic fluid index (AFI) was significantly late onset in idiopathic factor. Diabetes, gestational or pre-existing, was present in all of women (ten cases) in maternal factor. Higher AFI was found to be associated with an increased frequency of prenatally detected congenital anomalies. Abnormal fetal karyotype noted in 18/45 (40%) cases of polyhydramnios. Polyhydramnios diagnosed on ultrasound requires further maternal and fetal diagnostic tests.