Isolation of Bacteriophages Active Against Neisseria meningitidis

Abstract

Five distinct bacteriophages have been isolated from strains of Neisseria meningitidis . Filtrates with titers of 10 −4 to 10 −6 were produced with a modified Swanstrom and Adams semisolid agar procedure, employing Eugonbroth with added agar and an incubation temperature of 30 C. Of 49 strains of N. meningitidis (groups B and C), 25 were lysed by one or more of the phages, but there was no lysis of other Neisseria and Mima polymorpha strains.