Microglia P2X4 receptors as pharmacological targets for demyelinating diseases

  • Di Virgilio F
  • Sarti A
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Abstract

Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis. EMBO Mol Med (2018) 10: e9369

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Di Virgilio, F., & Sarti, A. C. (2018). Microglia P2X4 receptors as pharmacological targets for demyelinating diseases. EMBO Molecular Medicine, 10(8). https://doi.org/10.15252/emmm.201809369

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