A Review of Catecholamine Associated Cardiomyopathies and Channelopathies

Abstract

Conditions associated with states of catecholamine toxicity are pheochromocytoma, paraganglioma, Takotsubo's cardiomyopathy, and catecholaminergic polymorphic ventricular tachycardia. This article defines these conditions along with relevant diagnostic and prognostic factors. The role of catecholamines in these conditions are compared and contrasted. Emphasis is given to the role of endothelial dysfunction as a possible etiologic factor in cardiomyopathy associated with excess catecholamines.