MODELING OF DIELECTRIC PERMITTIVITY OF THE ERYTHROCYTES MEMBRANE AS A THREE-LAYER MODEL

Abstract

The dielectric theories which used for applications of dielectric spectroscopy to investigate heterogeneous systems, such as particle suspensions, membranes, and tissue are described in this article. The dielectric constant ε′ , the loss ε′′ , and the conductivity σ of substances in a broad frequency range (1 Hz to 1011 Hz), with for using a combination of different method of dielectric spectroscopy applied to identical samples was described. In the present work, we analyze the dispersion regions, commonly found in biological substances and tissue, usually as termed as α , β , δ and γ -dispersions. The nature of the dispersion caused by the membrane of RBCs in the radio frequency spectrum of the dielectric properties of blood which often is ascribed to the motion of bound water molecules is not yet fully understood. Dielectric properties of RBS membrane have been studied by means of the spheroidal model, where the three shells correspond to the double lipid bilayer and the spectrin network of the inner membrane, respectively. Based on the Maxwell-Wagner model and takes into account the morphological parameters of RBS membranes of cells using appropriate approximations the some simple relations was derived. In discussing the dielectric properties of RBS membrane was considered the mathematical model which accurately fit the experimental observations. Such models have obvious applications when characterizing the data and testing it against possible physical theories.