Electrocatalytic effect of Al2O3 supported on clay in oxidizing of ibuprofen at graphite electrode

Abstract

In this work, the electro-catalytic oxidation of ibuprofen was studied using aluminum oxide supported on clay (Clay/Al2 O3). The latter has been successfully prepared by impregnating aluminum particles in the clay by heat treatment. The electro-catalytic performances of Clay/Al2 O3 for the oxidation of ibuprofen were studied using cyclic voltammetry (CV), chronoamperometry, and differential pulse voltammetry (DPV) in 0.1 mol L-1 of the phosphate buffer (pH = 7). It has been shown that the proposed catalyst exhibits remarkably an electro-catalytic effect performance vis-a-vis the oxidation of ibuprofen. In addition, the peak oxidation currents depend linearly on the ibuprofen concentration in the wide ranges from 1.0·10-3 mol L-1 to 1.0·10-6 mol L-1 with a detection limit of 1.95·10-8 mol L-1 and response time of 30 second. Possible interferences were evaluated in 1.0·10-5 mol L-1 ibuprofen. The proposed catalyst also indicated suitable repeatability and stability. Besides, the proposed CPE-Clay/Al2 O3 has been successfully applied for ibuprofen analysis in human blood with good recoveries.