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Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer

Cell (2020) 183(5) 1202-1218.e25
DOI: 10.1016/j.cell.2020.10.016
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Abstract

The high level of innervation seen in pancreatic ductal adenocarcinoma tumors supplies serine and serine-deprived conditions promote tumor innervation to support growth in nutrient poor environments.

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Banh, R. S., Biancur, D. E., Yamamoto, K., Sohn, A. S. W., Walters, B., Kuljanin, M., … Kimmelman, A. C. (2020). Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer. Cell, 183(5), 1202-1218.e25. https://doi.org/10.1016/j.cell.2020.10.016

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