Abstract
Two major allergens - the house dust mite Dermatophagoides pteronyssinus (Der p 1) and cockroach allergens - are proteolytically active and stimulate the protease-activated receptor 2 (PAR-2). Jeong et al. (2008, this issue) exposed mouse and human epidermis to both allergens and correlated the observed delay in permeability barrier recovery to PAR-2 activation/signaling. This article exposes the secretive boundaries between barrier homeostasis and immunity. © 2008 The Society for Investigative Dermatology.
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CITATION STYLE
Roelandt, T., Heughebaert, C., & Hachem, J. P. (2008). Proteolytically active allergens cause barrier breakdown. Journal of Investigative Dermatology. Nature Publishing Group. https://doi.org/10.1038/jid.2008.168
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