Direct C(sp2)-H amination of aryl aldehyde-derived hydrazones via visible light promoted photoredox catalysis

Abstract

An unprecedented visible-light-induced direct C(sp2)-H amination of aryl aldehyde-derived hydrazones was developed by using N-acyloxyphthalimides as nitrogen-radical precursors. This reaction represents a new way to substituted hydrazones with amination of carbon-nitrogen π bonds. A radical C-H amination mechanism is proposed.