Abstract
The MRL mouse is the only known strain of mouse that can regenerate cardiac lesions and completely heal ear punches without scarring. To determine if the MRL also has greater regeneration capabilities in amputated digit tips, right paw digit tips of neonatal mice were dissected, with the left front paws as uncut controls. Controls used for regeneration comparison were the DBA, B6, C3H, and 129 inbred mouse strains. Consecutive X-ray images were captured of the left and right paws at 0, 7, 14, 21, and 28 days postamputation. MRL mouse digit tips regenerated greater in comparison to all strains tested (p?
Cite
CITATION STYLE
Chadwick, R. B., Bu, L. M., Yu, H., Hu, Y., Sachdev, R., Tan, Q. W., … Baylink, D. J. (2008). 038 Digit Tip Regeneration and Global Gene Expression Profiling in the MRL SuperHealer Mouse. Wound Repair and Regeneration, 13(2), A4–A27. https://doi.org/10.1111/j.1067-1927.2005.130215al.x
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