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Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the O-Linked N-Acetylglucosamine transferase (OGT)

Journal of Biological Chemistry (2015) 290(8) 4801-4812
DOI: 10.1074/jbc.M114.605881
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Abstract

Background: TET proteins oxidize 5-methylcytosine and contribute to active DNA demethylation.

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Bauer, C., Göbel, K., Nagaraj, N., Colantuoni, C., Wang, M., Müller, U., … Leonhardt, H. (2015). Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the O-Linked N-Acetylglucosamine transferase (OGT). Journal of Biological Chemistry, 290(8), 4801–4812. https://doi.org/10.1074/jbc.M114.605881

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