Integrin

Abstract

Integrins are a group of heterodimers in vertebrates consisting of 24 different transmembrane receptors. Integrins are the most important group among cell adhesion receptors, and also one of the most numerous groups of external membrane receptors. They are present virtually in every cell of the body, except for red blood cells. The main focus of this chapter was on their structural and biochemical features. The studies were mainly conducted using antibodies and the ligand binding mechanism in terms of mutations. In the cellular signals still hide many unknowns.