Emerging Therapies for Esophageal Cancer

Abstract

This chapter will review the status of clinical and laboratory research exploring targeted therapies for treatment of esophageal cancer. Therapies that target specific pathways activated in cancers offer the potential for potent anti-cancer effects with minimal host toxicity. This review will not only summarize the status of targeted therapies currently being evaluated in clinical trials for treating esophageal cancer, but also discuss therapies that show promise in pre-clinical studies, including those that target metabolic pathways in cancer.