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On-chip alginate microencapsulation of functional cells

Macromolecular Rapid Communications (2008) 29(2) 165-170
DOI: 10.1002/marc.200700641
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Abstract

We report the use of a PTFE-based microfluidic device for the encapsulation of living, therapeutically-active cells within monodisperse alginate microspheres. We present a novel microfluidic platform and a flexible experimental method for the production of alginate microspheres. Cell lines HEK293, U-2 OS and PC12 were separately encapsulated using this method, with minimal loss of cell viability. © 2008 WILEY-VCH Verlag GmbH & Co. KGaA.

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Workman, V. L., Dunnett, S. B., Kille, P., & Palmer, D. D. (2008). On-chip alginate microencapsulation of functional cells. Macromolecular Rapid Communications, 29(2), 165–170. https://doi.org/10.1002/marc.200700641

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