Prediction of HIV drug resistance based on virologic, immunologic, clinical, and/or adherence criteria in the stratall ANRS 12110/ESTHER trial in Cameroon

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Abstract

Our study in Cameroonian rural district hospitals showed that the immunologic and clinical failure criteria had poor performance to identify human immunodeficiency virus drug resistance in a timely manner. Switching to second-line antiretroviral therapy after 2 consecutive viral loads ≥5000 copies/mL, as recommended by the World Health Organization, appeared to be the most appropriate strategy. © The Author 2013.

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Boullé, C., Kouanfack, C., Laborde-Balen, G., Aghokeng, A. F., Boyer, S., Carrieri, M. P., … Laurent, C. (2013). Prediction of HIV drug resistance based on virologic, immunologic, clinical, and/or adherence criteria in the stratall ANRS 12110/ESTHER trial in Cameroon. Clinical Infectious Diseases, 57(4), 604–607. https://doi.org/10.1093/cid/cit323

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