Three new taxanes with the 10-alkoxy group from the heartwood of Taxus cuspidata

Abstract

Three novel taxanes with the 10-alkoxy group were isolated from heartwood of Taxus cuspidata. The structures were identified as 2α,14β- diacetoxy-10β-ethoxytaxa-11,4(20)-dien-5α-ol (1), 2α,14β-diacetoxy-10β-methoxytaxa-11,4(20)-dien-5α-ol (2), and 2α-acetoxy-10β-ethoxytaxa-11,4(20)-diene-5α,14β-diol (3) on the basis of spectroscopic analysis. These are the first taxanes with an alkoxy moiety on the skeleton.