Abstract
Four new steroid saponins 1-4 were isolated from the rhizomes of Anemarrhena asphodeloides (Asparagaceae), as well as four known saponins: anemarsaponin B (5) timosaponin D (6), timosaponin E1 (7) anemarsaponin B II (8). Their structures were established through UV and NMR as well as MS data. All the compounds were evaluated for cytotoxicity against HepG2 and SGC7901 human cancer lines. Compounds 3 and 7 displayed medium antiproliferative activities on HepG2 and SGC7901 cells, with IC50 values of 43.90 and 57.90 μM, respectively.
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Yang, B. Y., Zhang, J., Liu, Y., & Kuang, H. X. (2016). Steroidal saponins from the rhizomes of Anemarrhena asphodeloides. Molecules, 21(8). https://doi.org/10.3390/molecules21081075
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