Urea decomposition: Efficient synthesis of pyrroles using the deep eutectic solvent choline chloride/urea

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Abstract

A simple and efficient method is reported for the synthesis of pyrroles via condensation of a series of tricarbonyl compounds with ammonia, which was generated in situ from decomposition of the deep eutectic solvent choline chloride/urea.

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Hu, L., Luo, J., Lu, D., & Tang, Q. (2018). Urea decomposition: Efficient synthesis of pyrroles using the deep eutectic solvent choline chloride/urea. Tetrahedron Letters, 59(18), 1698–1701. https://doi.org/10.1016/j.tetlet.2018.03.043

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