Asymmetric synthesis of β-amino acids: Dynamic kinetic resolution utilizing 2-oxoimidazolidine-4-carboxylate as a chiral auxiliary

  • Nunami K
  • Kubo A
  • Kubota H
  • et al.
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Abstract

A symposium report. The reaction of chiral auxiliary 2-oxoimidazolidine-4-carboxylate I (R = Me, Et, iso-Bu) with NaCH(CO2R)2 (R = Me, CH2Ph) can be applied to the asym. synthesis of a variety of optically active β-amino acids. [on SciFinder(R)]

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Nunami, K., Kubo, A., Kubota, H., & Takahashi, M. (2006). Asymmetric synthesis of β-amino acids: Dynamic kinetic resolution utilizing 2-oxoimidazolidine-4-carboxylate as a chiral auxiliary. In Peptide Science — Present and Future (pp. 752–754). Kluwer Academic Publishers. https://doi.org/10.1007/0-306-46864-6_256

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