Severe Hypothyroidisman Early Complication of Lithium Therapy

Abstract

It is well recognized that treatment with lithium may cause thyroid abnormalities. Non-toxic goitre and impairment of thyroid function detectable by biochemical tests but without clinical manifestations have been reported. Overt hypothyroidism is uncommon. The following case is noteworthy in view of the rapid development and subsequent regression of clear-cut hypothyroidism during and after a short course of lithium treatment. © 1972, British Medical Journal Publishing Group. All rights reserved.