Electrochemistry of DNA at Single-Wall Carbon Nanotubes

Abstract

Single-wall carbon nanotubes (SWNTs) can be used as an electrochemical probe to study the electrochemical oxidation of DNA, two voltammetric oxidation peaks corresponding to electrochemical oxidation of guanine and adenine residues in DNA could be observed, demonstrating a new potential application of SWNTs in DNA analysis. Compared to other types of electrode materials, the electrochemical response of natural DNA was greatly enhanced at the SWNT-modified electrode. This method can be used to investigate the interaction of SWNTs with DNA.