Synthesis of novel derivatives of 4-amino-3,5-dicyanopyrazole

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Abstract

Diazotisation of substituted arylamines followed by reaction with malononitrile gave substituted arylazomalononitriles. Cyclisation of these intermediates with chloroacetonitrile and triethylamine, as base, gave the corresponding new aminoclicyanopyrazoles, in 22-80% yields.

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Gonçalves, M. S. T., Oliveira-Campos, A. M. F., Rodrigues, L. M., Proença, M. F. R. P., Griffiths, J., Maia, H. L. S., … Hrdina, R. (2004). Synthesis of novel derivatives of 4-amino-3,5-dicyanopyrazole. Journal of Chemical Research, (2), 115–117. https://doi.org/10.3184/030823404323000396

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