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Ubiquitin Variant Inhibitors Meet the Deubiquitinase USP15

Structure
DOI: 10.1016/j.str.2019.03.011
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Abstract

Deubiquitinases (DUBs) are important regulators of cellular function and selective inhibitors are required to reveal their biological role and therapeutic potential. In this issue of Structure, Teyra et al. (2019) report the development of DUB USP15 inhibitors that provide a starting point for the analysis of USP15 function.

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Middleton, A. J., & Day, C. L. (2019, April 2). Ubiquitin Variant Inhibitors Meet the Deubiquitinase USP15. Structure. Cell Press. https://doi.org/10.1016/j.str.2019.03.011

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