Determination of polyhexamethylene biguanide hydrochloride

Abstract

Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used as a disinfectant in personal care products such as cosmetics and toiletries and as a sanitizer in swimming pools. PHMB-HCl possesses marked characteristics of cationic polyelectrolytes. We have applied unique determination methods to PHMBHCl using its ion association with organic anions and polyanion. In this review, we provide several colloidal titrations and a voltammetric method.