Soluble single-molecule nanogels of controlled structure as a matrix for efficient artificial enzymes

Abstract

(Figure Presented) Copy cats! Soluble single-molecule nanogels (see STEM micrograph; scale-bar = 20 nm) with a densely packed structure are prepared by a new method, and for the first time efficient molecular imprinting is possible. These nanogels with defined molecular weights of, for example, 40 000 Da, low polydispersities, and on average one active site per particle proved to be catalytically active enzyme mimics. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.