Sarcoma de Kaposi iatrogénico diseminado con debut en encía maxilar: a propósito de un caso.

Abstract

ABSTRACT Kaposi's Sarcoma (KS) is a multifocal neoplasm of cells derived from the lymphatic endothelium infected with the Human Herpes Virus 8 (HHV-8). Four clinical subtypes are described, which are histologically indistinguishable, differ in epidemiology and prognosis: classic, iatrogenic, endemic and epidemic. Involvement of the oral cavity is rare in the iatrogenic type and exceptional as a clinical debut. The diagnosis requires histological confirmation with immunohistochemistry. Oral involvement is associated with disseminated disease, with diagnostic suspicion and biopsy taking being essential for early diagnosis and correct staging, due to the important therapeutic and prognostic implications. The clinical case of a 41-year-old male evaluated for a tumor in the attached gingiva with previous periodontal treatment and a history of kidney transplantation is described. Excisional biopsy was performed with a diagnosis of KS, which after completing the study confirmed disseminated iatrogenic-type KS requiring a change in immunosuppressive medication and 6 cycles of chemotherapy treatment with complete response.