Reaction of N,N '-disubstituted hydrazinecarbothioamides with 2-bromo-2-substituted acetophenones

Abstract

Reaction of hydrazinecarbothioamides with 2-bromoacetophenones furnished the formation of thiazole-, bisthiazole-, pyrazole- and 1,3,4-thiadiazole- derivatives in good yields. The mechanism was discussed. The structures of products were proved by MS, IR, NMR, elemental analyses and X-ray structure analyses.