Abstract
The activities of cefotaxime and minocycline against Aeromonas hydrophila were investigated. Cefotaxime (4 times the MIC) plus minocycline (0.75 times the MIC) elicited an inhibitory effect for 48 h in a time-kill study, and more infected mice treated with both drugs survived (91%) than survived after treatment with cefotaxime (9%) or minocycline (44%) alone, suggesting that cefotaxime and minocycline act synergistically against A. hydrophila.
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CITATION STYLE
Ko, W. C., Lee, H. C., Chuang, Y. C., Ten, S. H., Su, C. Y., & Wu, J. J. (2001). In vitro and in vivo combinations of cefotaxime and minocycline against Aeromonas hydrophila. Antimicrobial Agents and Chemotherapy, 45(4), 1281–1283. https://doi.org/10.1128/AAC.45.4.1281-1283.2001
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