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Host-guest interaction of cucurbit[8]uril with n-(3-aminopropyl)cyclohexylamine: Cyclohexyl encapsulation triggered ternary complex

Molecules (2018) 23(1)
DOI: 10.3390/molecules23010175
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Abstract

The host-guest interaction of a series of cyclohexyl-appended guests with cucurbit[8]uril (Q[8]) was studied by1H NMR spectroscopy, isothermal titration calorimetry (ITC), and X-ray crystallography. The X-ray structure revealed that two cycloalkane moieties can be simultaneously encapsulated in the hydrophobic cavity of the Q[8] host to form a ternary complex for the first time.

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Xia, Y., Wang, C. Z., Tian, M., Tao, Z., Ni, X. L., Prior, T. J., & Redshaw, C. (2018). Host-guest interaction of cucurbit[8]uril with n-(3-aminopropyl)cyclohexylamine: Cyclohexyl encapsulation triggered ternary complex. Molecules, 23(1). https://doi.org/10.3390/molecules23010175

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