Chemical constituents of MeOH extract from the fruits of Macaranga sampsonii

Abstract

The genus Macaranga belongs to the family Euphorbiaceaeconsistingof about 300 species that are mainly distributed inthe tropics of Africa, Asia, Australia, and the Pacific regions. Thirteen different species of this genus occur in Viet Nam, and Macaranga sampsonii has been used in traditional medicine to treat swellings, cuts, sores. Phytochemical investigation of the methanol extract of Macaranga sampsonii led to the isolation of six compounds including: boehmenan X (1), maltol β-D-glucopyranoside (2), methyl brevifolincarboxylate (3), scopoletin (4), 3,5-dihydroxy-4-methoxy benzoic acid (5) and gallic acid (6). Their structures were confirmed by spectroscopic methods including IR, MS, 1D, 2D NMR and compared to previous reported spectral data values.