Pharmacists' Knowledge of Non-Sterile Good Compounding Practice (GCP) and Its Implementation in Balikpapan Community Health Centers: A Cross-Sectional Study

Abstract

Introduction: Good Compounding Practice (GCP) is a guide to compounding drugs that contains more in-depth instruction on implementing good compounding practices to prepare compounded drug formulations that will be given to patients. Poorly conducted compounding can reduce quality, including uniformity of content/levels and weights, impaired stability in both physical, chemical and biological, and the risk of drug interactions and side effects. This study aims to determine the level of pharmacist knowledge about GCP, and GCP implementation. Methods: This type of research is the descriptive correlation with a cross-sectional research design. The object of this research is to the level of knowledge of pharmacists in all Health Centers of Balikpapan City about GCP, and its implementation. The sampling technique used in this research is total sampling technique, then data analysis to determine the correlation between knowledge level and implementation using chi-square analysis. Results: The results showed that the level of pharmacist knowledge about GCP was classified as good, with an average of 87.78. Implementation of GCP by pharmacists is also good with an average value of 83.10. No significant relationship was found between the level of knowledge and the implementation of Good Compounding Practice (GCP) with a P value 0f 0.484. Conclusion: There is no significant relationship between pharmacists' knowledge of Good Compounding Practice (GCP) and its implementation in Balikpapan City Health Centers.