Emerging importance of holobionts in evolution and in probiotics

40Citations
Citations of this article
147Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

The existence of microbe free animals or plants in nature is virtually impossible as they and plants have a certain degree of symbiotic association with microbes. This symbiotic association leads to the formation of holobiont (host and its symbionts). This mutual coexistence is not merely at the physical or chemical level but also at the genetic level leading to the emergence of the concept of hologenome (gene pool of host and its associated symbionts). The abundance of symbionts with the associated gene diversity contributes to the fitness of the holobiont under varying environmental conditions. The hologenome theory of evolution considers the dynamic holobiont as a single unit for natural selection and provides a more accommodating view of evolution blending Darwinism and Lamarkism. Additionally, holobionts are providing scientific basis to our understanding of the growing importance of probiotics in human health and in disease management. © 2013 Singh et al.; licensee BioMed Central Ltd.

Cite

CITATION STYLE

APA

Singh, Y., Ahmad, J., Musarrat, J., Ehtesham, N. Z., & Hasnain, S. E. (2013). Emerging importance of holobionts in evolution and in probiotics. Gut Pathogens. https://doi.org/10.1186/1757-4749-5-12

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free