Synthesis of dicationic 2,5-diarylpyrroles

Abstract

A new series of dicationic reversed amidine derivatives 4a-f and a substituted guanidine analog 7 of 2,5-diarylpyrrole obtained starting from the corresponding 2,5-bis(aminoaryl)pyrroles 3a-c are reported. The results of DNA binding studies and antimicrobial screening assays for these compounds are presented.