Efficacy of silver nanoparticles synthesized on Commiphora gileadensis (Balsam) extract against infectious bacteria

Abstract

Compare to the other metal ion, silver nanoparticles has wide application in the field of microbiology and pharmacology drug. The aim of present study was to synthesize cheap and eco-friendly silver nanoparticles on Commiphora gileadensis extract and evaluate its antimicrobial properties against selected bacterial strains. Aqueous extract of C. gileadensis was used for the synthesis of silver nanoparticles. These synthesized nanoparticles were characterized by using UV spectrophotometer, scanning electron microscope (SEM) and EDX. The characterization of AgNPs was carried out by uv-vis spectrum at λmax = 435 nm and the peak was correlated to the plasmonic nature of the particles as reported by number of earlier reports. In addition, EDX spectrum has been showed four peaks corresponding to the silver, zinc, carbon and oxygen. The results of present study indicated that the plant extract has very important role in the synthesis of AgNPs. Antibacterial activity of nanoparticles was evaluated using CFU method against E.coli O157:H7 and Methicillin-resistant Staphylococcus aureus (MRSA). Synthesized nanoparticles exhibit significant antibacterial activity against the infectious bacteria.