Rapid autologous point-of-care transplantation of the adipose-derived stromal vascular fraction in a dog with cubarthrosis

Abstract

A 1-year-old shepherd dog was presented in the veterinary hospital due to left-sided cubarthrosis and persisting weight-bearing lameness of the left forelimb after a fragmented coronoid process in the left elbow joint had been removed at the age of 6 months. An autologous point-of-care transplantation of adipose tissue-derived regenerative cells was performed using ARC System (InGeneron, Houston, TX, USA). Pre- and postoperative investigations included orthopaedic and radiographic examinations, gait analyses as well as two owner questionnaires, Liverpool Osteoarthritis in Dogs and Canine Brief Pain Inventory. After 1, 2, 3, 6 and 12 months of treatment, the dog showed an improvement of peak vertical force and vertical impulse in the gait analyses as well as. The Canine Brief Pain Inventory and the Liverpool Osteoarthritis in Dogs revealed an improvement of the quality of life within all further control visits up to 12 months after the therapy.